basic FUNCTION
| ATP-dependent RNA helicase activity |
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involved in translation initiation on mammalian mRNAs with structured 5prime UTRs (Pisareva 2008) |
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DExH-box protein, facilitating translation initiation on mRNAs with structured 5prime untranslated regions (Stevenson 2008) |
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translation initiation factor, required for cell proliferation, that potentially can be exploited as a target to inhibit cancer cell growth (Parsyan 2009) |
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cytoplasmic protein that associates with the 40S ribosomal subunit (Parsyan 2009) |
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plays a prominent role in the translation of mRNAs with highly structured 5prime UTRs (Parsyan 2009) |