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FLASH GENE
Symbol KRT23 contributors: mct/npt - updated : 27/09/2008
HGNC name keratin 23 (histone deacetylase inducible)
HGNC id 6438
EXPRESSION
Type widely
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivefemale systemplacenta  highly
Respiratoryrespiratory tractlarynx  highly
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period pregnancy
Text placenta
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a rod domain
  • mono polymer heteromer , tetramer , complex
    HOMOLOGY
    Homologene
    FAMILY
  • intermediate filament family
  • type I keratin family
  • CATEGORY structural protein
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytoskeleton,intermed filament
    basic FUNCTION
  • responsible for the structural integrity of epithelial cells
  • epithelial keratins associated with simple/glandular or stratified, non-cornified epithelia
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    induced by thrichostatin A
    histone deacetylase inhibitors (sodium butyrate NaBu) in pancreatic cancer cells
    p21 (itself induced by Nabu)
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS