basic FUNCTION
| may mediate protein-protein interactions |
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required for both cerebellar and cortical development |
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regulates cilium formation via its interaction with RAB8A, a small GTPase critical for polarized membrane trafficking |
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may be a protein that is present only in a subset of ciliated cells that may be involved in the regulation or trafficking of proteins necessary for the formation and/or functioning of different subtypes of cilium with presumed independent functions |
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potential involvement of AHI1 in the maintenance of glucose homeostasis and type 2 diabetes mellitus progression |
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role in photoreceptor development |
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required for both cerebellar and cortical development |
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potential role for Jouberin (Jbn), the protein encoded by AHI1, in canonical Wnt signaling |
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AHI1 and CDKN1C exhibit opposite expression patterns, where AHI1 is expressed in poor and intermediate prognosis patients, while CDKN1C is expressed in favourable prognosis patients |