Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | POLR1A | contributors: SGE/npt - updated : 21-06-2023 |
HGNC name | polymerase (RNA) 1 polypeptide A, 194kDa |
HGNC id | 17264 |
|
EXPRESSION |
Type | ubiquitous |
expressed in | (based on citations) |
organ(s) |
cell lineage
cell lines
| fluid/secretion
| |
at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
motifs/domains
![]() |
conjugated | PhosphoP |
HOMOLOGY |
interspecies | homolog to murine Polr1a (87.1pc) |
homolog to rattus Polr1a (88.4pc) |
Homologene |
FAMILY |
CATEGORY | enzyme |
SUBCELLULAR LOCALIZATION
| intracellular |
intracellular,cytoplasm | |
intracellular,nucleus,nucleoplasm | |
intracellular,nucleus,chromatin/chromosome | |
intracellular,nucleus,nucleolus |
CELLULAR PROCESS
|
nucleotide, transcription |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism | purine/pyrimidine |
signaling |
a component |
INTERACTION |
DNA | DNA binding |
RNA |
small molecule | metal binding, |
|
protein |
cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) | AFD3 , NDCFL , ACCAL |
Susceptibility |
Variant & Polymorphism
![]() |
Candidate gene
Marker
| Therapy target
|
| |
ANIMAL & CELL MODELS |