basic FUNCTION
| involved in the control of cellular response to growth factors and adhesion factors |
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may contribute to development and/or progression of lymphomas and other tumors |
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may play a role in the context of sarcomagenesis, in enhancing FGF signaling that leads to mesodermal cell proliferation without induction of myogenic differentiation |
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stimulates the proliferation of rhabdomyosarcoma cells, and its stimulatory activity is a result of its ability to promote Hedgehog (Hh) signaling |
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stimulates Hh signaling by facilitating/stabilizing the interaction between Hh and PTCH1 |