basic FUNCTION
| conserved nuclear factor required for innate immune responses |
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promotes sustained ERK1/2 activation through repression of MAKP1 transcription, resulting in promotion of tumorigenicity and metastasis |
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plays an important role in oncogenesis of LLC1 lung carcinoma cells, an may also serve as an oncogene in other cancers |
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important nuclear factor which plays functions in innate immune response, myogenesis, muscle development, and carcinogenesis |
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nuclear protein, bridging NFKB1 and the chromatin remodeling SWI/SNF complex by interacting with SMARCD proteins as well as NFKBIZ, which forms a complex with the NFKB1 p50 subunit |
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is critical for inducing inflammatory genes by bridging NFKBIZ and the SWI/SNF complex |