basic FUNCTION
| tyrosine phosphorylated effector of EGF-mediated cell signaling, associated with microtubule-based structures and may play roles in the developing and adult inner ear |
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not involved in the crucial steps of mitosis |
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involved in EGFR signaling |
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functions as a novel inhibitor for the down-regulation of the EGF receptor and plays a crucial role for regulating the amount of the EGF receptor on the cell surface membrane ( |
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likely to be a negative regulator for the NF-kappaB signaling pathway |
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required for survival in chronic lymphocytic leukemia (CLL) and mantle cell lymphoma (MCL) cells and controls NFkappaB signaling |
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acting as a regulator downstream of several receptors and functioning as a positive or negative regulator in a signaling pathway-dependent manner |