basic FUNCTION
| may be functioning during G1 and S phase of the cell cycle and suppress growth |
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involved in TERT regulation |
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affects pancreatic beta cell number during embryogenesis and early in life, but is probably redundant for beta cell number and function in adult animals under normal conditions |
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acts as a bona fide tumor suppressor gene through the mechanism of regulating PTEN protein stability and function |
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both FRK and PTK6 have been implicated in the regulation of epithelial cell differentiation and apoptosis |
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has tumor suppressor functions in mammary gland cells |
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VEGFA and extracellular collagen matrix (FRK/COL10A1) pathways contribute to the development of advanced age-related macular degeneration |
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may play a protective role against the progression of glioma by suppressing cell migration and invasion |