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FLASH GENE
Symbol TMEM260 contributors: mct - updated : 10-05-2017
HGNC name chromosome 14 open reading frame 101
HGNC id 20185
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Visualeyeuveachoroid  
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialbarrier/liningretinal pigment epithelium (RPE)  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • C terminus of the protein might confer subcellular localization specificity or indeed a discrete functionality in one of the organellar membranes
  • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION unknown
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) CRDS
    Susceptibility
  • to overall survival in non-Hodgkin lymphoma (NHL)
  • Variant & Polymorphism SNP
  • rs4901706, located in the 3prime UTR of TMEM260, was shown to be independently related to overall survival in non-Hodgkin lymphoma (NHL) patients
  • Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS