Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol TAS2R38 contributors: mct - updated : 10-10-2011
HGNC name taste receptor, type 2, member 38
HGNC id 9584
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivemouthtongue   
digestivemouthpalate   
Nervousbrainforebraincerebral cortex   Homo sapiens
 brainhindbraincerebellum   Homo sapiens
cells
SystemCellPubmedSpeciesStageRna symbol
Digestiveepithelial cell Homo sapiens
Gustatoryclear receptor cell
Respiratoryepithelial cell Homo sapiens
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • seven transmembrane segments(7TM) receptor
  • an extracellular ligand binding domain
  • conjugated GlycoP
    HOMOLOGY
    interspecies ortholog to murine Tas2r138
    homolog to rattus T2R38
    Homologene
    FAMILY G-protein coupled receptor T2R family
    CATEGORY signaling neurotransmitter , receptor membrane G
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • directly influencing on phenylthiocarbamide taste sensitivity and involved in bitter perception
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    text G-protein coupled receptor protein signaling pathway
    PATHWAY
    metabolism
    signaling signal transduction , sensory transduction/taste
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    constitutional        
    good taster
    constitutional        
    non-taster
    Susceptibility
    Variant & Polymorphism other
  • haplotype Pro-Ala-Val associated with phenotype good taster
  • haplotype Arg-Val-Isoleu associated with phenotype non-taster
  • Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS