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FLASH GENE
Symbol PHF5A contributors: - updated : 07-03-2005
HGNC name PHD finger protein 5A
HGNC id 18000
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrain    
Urinarykidney    
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
a PHD-finger-like domain that is flanked by highly basic N- and C-termini
HOMOLOGY
Homologene
FAMILY PHD-finger superfamily
CATEGORY DNA associated , transcription factor
SUBCELLULAR LOCALIZATION     intracellular
intracellular,nucleus,nucleoplasm
basic FUNCTION
  • maybe acting as a chromatin associated protein
  • small nuclear protein that enhances the response of the connexin 43 gene to estrogen
  • playing a role in the cellular response to estrogen affecting both AF-1 and AF-2 activities of the estrogen receptor alpha
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    activated by estrogen in the myometrium
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS