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FLASH GENE
Symbol ZNF366 contributors: mlc - updated : 07-11-2007
HGNC name zinc finger protein 366
HGNC id 18316
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivepharynx   highly
Lymphoid/Immunethymus   highly
Reproductivefemale systemplacenta  highly
Respiratoryrespiratory tracttrachea  highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • eleven zinc finger motifs of the C2H2 type
  • a proline-rich region
  • an acidic region
  • conjugated MetalloP
    HOMOLOGY
    interspecies homolog to murine DC- script (80 p 100)
    Homologene
    FAMILY zinc finger protein family
    CATEGORY regulatory , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome
    basic FUNCTION
  • ESR1-interacting protein, which is a potent corepressor of ESR1 activity
  • may play an important role in regulating the expression of genes in response to estrogen
  • dendritic cell marker that could be involved in transcriptional repression
  • CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
    Zn2+
    protein
  • PLAG1
  • interacting with ESR1
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS