basic FUNCTION
| ZFR is a native component of STAU2-containing granules and likely plays its role during early steps of RNA transport and localization |
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is involved in the regulation of growth and cancer development |
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critical role of ZFR in NSCLC tumor growth and metastasis, by targeting the NOTCH1 signaling pathway |
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ZFR represses the interferon response by regulating alternative pre-mRNA splicing |
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regulation of ZFR in macrophage differentiation guards against aberrant interferon responses, suggesting a network of mRNA processing and decay that shapes the transcriptional response to infection |