protein
| ZDHHC6, which modifies key proteins of the endoplasmic reticulum, is controlled by an upstream palmitoyltransferase, ZDHHC16, revealing the first palmitoylation cascade |
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SELENOK interacts with an enzyme in the ER membrane,ZDHHC6 and the SELENOK/ZDHHC6 complex catalyzes the transfer of acyl groups such as palmitate to cysteine residues in target proteins, i.e., palmitoylation |
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MTDH is palmitoylated at residue cysteine 75 (Cys75), by ZDHHC6 as a palmitoyltransferase and this palmitoylation regulates its biological activity |