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FLASH GENE
Symbol SLC4A1AP contributors: mct/npt - updated : 17-04-2010
HGNC name solute carrier family 4 (anion exchanger), member 1, adaptor protein
HGNC id 13813
EXPRESSION
Type widely
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Urinarykidneytubulecollecting duct highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
  • solute carrier family 4
    • CATEGORY adaptor , transport carrier
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria
    intracellular,nucleus
    text mitochondrial localization (Hubner 2003)
    basic FUNCTION
  • may have a signalling role in the nucleus (Hubner 2002)
  • highly mobile nucleocytoplasmic shuttling and multilocalizing protein, having nuclear export activity (Hubner 2003)
  • adaptor protein or chaperone that may not be involved in the biosynthesis and targeting of SLC4A1 (Kittanakom 2004)
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • binding activity to the cytoplasmic domain of the kidney Na(+)-independent Cl(-)/HCO(-)(3) anion exchanger 1 (SLC4A1) (Hubner 2002)
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS