basic FUNCTION
| nuclear import of ribosomal protein |
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nucleocytoplasmic transport |
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required for cytoplasmic miRNA-guided gene silencing and affects nuclear localization of AGO proteins (EIF2C) (Weinmann 2009) |
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having specificity factor in the miRNA pathway, which may fulfill additional functions in nuclear Argonaute import (Weinmann 2009) |
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can influence nuclear import of Ago proteins in cells (Weinmann 2009) |
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plays a major role in Ago-mediated gene silencing and in the cytoplasm, localizes together with Ago proteins to P bodies and is involved in efficient loading of Ago proteins onto a variety of different target mRNAs (Weinmann 2009) |
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contribute to the coordination of several critical steps of cerebral cortex development |
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plays a critical and non-redundant role in TGFB1 signaling during development |
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is a nuclear transport receptor |
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translocates cargo molecules such as proteins, RNAs, and ribonucleoprotein complexes into the nucleus in a RanGTP-dependent manner |