motifs/domains
| a transposase domain at the C-terminus |
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9 C2H2-type zinc fingers |
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a zinc-finger-like motif, CBX5-binding domain, essential for normal mitotic progression and dissociation of CBX5 from mitotic chromosome arms, HP1-binding zinc-finger-like motif (amino acids 791–850) thought to be integral for the binding of POGZ to heterochromatin protein 1 (CBX5, or HP1) for proper mitotic progression |
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a CENPB-type DNA-binding domain |
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five functional domains |
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a centromere protein (CENP) B-like DNA-binding domain, |
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a DDE domain that might regulate gene expression |