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FLASH GENE
Symbol NUDT13 contributors: mct - updated : 02-06-2022
HGNC name nudix hydrolase 13
HGNC id 18827
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Urinarykidney    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / hematopoieticbone marrow   
cell lineage
cell lines
fluid/secretion blood
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • mutT domain
  • a sequence motif characteristic of the NADH pyrophosphohydrolase subfamily of Nudix hydrolases
  • HOMOLOGY
    interspecies homolog to murine Nudt13
    Homologene
    FAMILY NUDIX family of hydrolases
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria,matrix
    basic FUNCTION
  • nucleoside triphosphate pyrophosphohydrolase activity
  • may act to regulate the concentration of mitochondrial reduced pyridine nucleotide cofactors and the NAD(P)+/NAD(P)H ratio in mitochondria
  • potentiial role in the regulation of NAD(P)H pools
  • both the uncharacterized MFSD4A and NUDT13 may have a role in the regulation of the epithelial-mesenchymal transition (EMT)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS