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FLASH GENE
Symbol EML2 contributors: - updated : 03-03-2007
HGNC name echinoderm microtubule associated protein like 2
HGNC id 18035
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveesophagus   highly
Endocrineparathyroid   highly
Lymphoid/Immunethymus   highly
Nervousbrain    
Reproductivemale systemprostate   
Respiratoryrespiratory tractlarynx  highly
Urinarykidney    
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period fetal, pregnancy
Text placenta, spleen
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • 11 WD repeats
  • a highly conserved hydrophobic ELP domain
  • HOMOLOGY
    Homologene
    FAMILY EMAP family of WD-repeat proteins
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION extracellular
        plasma membrane
        intracellular
    intracellular,nucleus,chromatin/chromosome
    text mitotic apparatus
    basic FUNCTION
  • may be modifying the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS