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FLASH GENE
Symbol CRLS1 contributors: mct - updated : 05-07-2007
HGNC name cardiolipin synthase 1
HGNC id 16148
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver   highly
 salivary gland   highly
 stomach   highly
Reproductivemale systemprostate  moderately
Respiratorylung   highly
Urinarykidney   highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Connectiveadipose  moderately
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to murine Crls1 (86.67 pc)
homolog to chimpanzee CRLS1 (100.00 pc)
Homologene
FAMILY CDP-alcohol phosphatidyl transferase family
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,mitochondria
text
  • intergrated to mitochondrial menbrane
  • basic FUNCTION
  • having a transferase activity
  • catalysing the synthesis of the mitochondrial phospholipid cardiolipin from cytidine diphosphate-diacylglycerol and phosphatidylglycerol
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism lipid/lipoprotein
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS