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FLASH GENE
Symbol CDK5RAP1 contributors: - updated : 21-08-2007
HGNC name CDK5 regulatory subunit associated protein 1
HGNC id 15880
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart    
Digestiveintestinesmall intestine  highly
Endocrinepancreas    
Lymphoid/Immunespleen   highly
 tonsils   highly
Nervousbrain    
Respiratorylung    
Urinarykidney    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialsecretoryglandularendocrine 
Epithelialsecretoryglandularexocrine 
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period pregnancy
Text placenta
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • the uncharacterized domain UPF0004
  • TRAM domain
  • C-terminal fragment bound with high affinity but was not inhibitory
  • HOMOLOGY
    interspecies homolog to Drosophila CG7187
    Homologene
    FAMILY
  • CDK5RAP1 subfamily
  • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION
    basic FUNCTION involved in the regulation of neuronal differentiation
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • binding to CDK5
  • interacts with CDK5R1
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS