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FLASH GENE
Symbol PRH1 contributors: - updated : 10-05-2006
HGNC name proline-rich protein HaeIII subfamily 1
HGNC id 9366
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver   moderately
 salivary gland   highly
Nervousbrain   moderately
Respiratoryrespiratory tractlarynx  highly
 respiratory tracttrachea  highly
Urinarykidney   highly
Visualeye   highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion salivary
at STAGE
PROTEIN
PHYSICAL PROPERTIES acid
STRUCTURE
motifs/domains proline-rich protein
HOMOLOGY
interspecies ortholog to murine Prp/Prh1
homolog to C.elegans Y67D8C.E
Homologene
FAMILY Hae III subfamily 1
CATEGORY secretory
SUBCELLULAR LOCALIZATION extracellular
basic FUNCTION
  • acting as highly potent inhibitors of crystal growth of calcium phosphates
  • providing a protective and reparative environment for dental enamel which is important for the integrity of the teeth
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS