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FLASH GENE
Symbol STMN4 contributors: - updated : 26-12-2005
HGNC name stathmin-like 4
HGNC id 16078
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrain    
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period embryo
Text neurons
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a N terminal domain with an hydrophobic extension, membrane-associated domain
  • a coiled-coil region
  • a C terminal stathmin-like domain, which promotes microtubule (MT) catastrophe and/or tubulin sequestering
    • HOMOLOGY
    interspecies homolog to murine Scgn10
    Homologene
    FAMILY SCG10/stathmin family proteins
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytoskeleton,microtubule
    intracellular,nucleus
    basic FUNCTION
  • able to depolymerize interphase microtubules when overexpressed
  • playing a role in differentiated neurons
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS development
    text neurogenesis
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS