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FLASH GENE
Symbol FEZ2 contributors: - updated : 29-03-2004
HGNC name fasciculation and elongation protein zeta 2 (zygin II)
HGNC id 3660
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
blood / hematopoieticspleen    
Cardiovascularheart    
Reproductivemale systemtestis   
Respiratorylung    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Lymphoid    
cells
SystemCellPubmedSpeciesStageRna symbol
Skin/Tegumentmelanocyte
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period pregnancy
Text placenta
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to C.elegans Unc76
intraspecies homolog to FEZ1
Homologene
FAMILY zygin family
CATEGORY signaling
SUBCELLULAR LOCALIZATION     plasma membrane
    intracellular
intracellular,nucleus
basic FUNCTION ; involved in axonal outgrowth and fasciculation
  • playing an important role in the morphological changes of various cells by associating with PRKCZ in a tissue-non-specific manner.
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS nervous system
    text axon guidance
    PATHWAY
    metabolism
    signaling signal transduction
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • synaptotagmin
  • PRKCZ
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS