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FLASH GENE
Symbol BBX contributors: mct/npt - updated : 19-09-2017
HGNC name bobby sox homolog (Drosophila)
HGNC id 14422
EXPRESSION
Type ubiquitous
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart     Homo sapiens
Digestivemouthtooth    Homo sapiens
Nervousbrainforebraincerebral cortex highly Homo sapiens
 brainlimbic systemhippocampus highly Homo sapiens
 brainhindbraincerebellum moderately Homo sapiens
Reproductivemale systemtestis  highly Homo sapiens
Urinarykidney   highly Homo sapiens
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / hematopoieticbone marrow    Homo sapiens
cells
SystemCellPubmedSpeciesStageRna symbol
Digestiveodontoblast Homo sapiens
cell lineage
cell lines neuronal tumor cell lines
fluid/secretion
at STAGE
physiological period embryo
Text developing CNS
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
CATEGORY transcription factor
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,cytosolic
intracellular,nucleus,nucleoplasm
basic FUNCTION
  • BBX plays an important role during the odontoblast differentiation of human DPSCs/progenitors
  • maybe associated with CNS development
  • CELLULAR PROCESS nucleotide, transcription
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • BBX is a downstream target of NFIX during development of the forebrain
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS