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FLASH GENE
Symbol CRNKL1 contributors: npt/mct - updated : 21/11/2008
HGNC name crooked neck pre-mRNA splicing factor-like 1 (Drosophila)
HGNC id 15762
EXPRESSION
Type ubiquitous
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivesalivary gland   highly
Respiratoryrespiratory tractlarynx  highly
 respiratory tracttrachea  highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • HAT (half-A-TPR) repeat
  • many tetratricopeptide repeats
  • HOMOLOGY
    interspecies ortholog to Drosophila crooked neck
    Homologene
    FAMILY
  • crooked-neck family
  • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,nucleoplasm,nuclear bodies,nuclear speckles
    text co-localizes with the SR and Sm protein splicing factors in discrete subnuclear domains implicated in snRNP biogenesis
    basic FUNCTION
  • essential for embryogenesis and is thought to be involved in cell cycle progression and pre-mRNA splicing
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS