basic FUNCTION
| involved in development and maintenance of kidney and liver structure and function |
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putative N-acetyltransferase that produces N-acetylaspartate in brain |
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involved in mercapturic acid formation |
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involved in mercapturic acid formation |
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catalyze transfer of an acetyl group from acetyl-coenzyme A to a wide range of acceptor substrates |
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NAT8 and NAT8B share enzymatic properties but differ in that NAT8B is post-translationally regulated via acetylation |
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important regulatory roles for NAT8B and NAT8 in neuron function with induction of NAT8 expression potentially serving as a critical event that adjusts the efficiency of the secretory pathway for activity-dependent neuronal functions |