basic FUNCTION
| functioning as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure |
|
implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA |
|
implicated in control of RNA stability and translation and selective cap-independent transcription |
|
playing a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability |
|
involved in the selective expression of cell survival factors through posttranslational events |
|
with CNBP, stimulate translation of the ornithine decarboxylase (ODC) internal ribosomal entry site (Gerbasi 2007) |
|
appeared to function as part of a larger holo-ITAF ribonucleoprotein complex (Gerbasi 2007) |
|
may play an important role in the IFNA response against HCV (hepatitis C virus) and may benefit the HCV clinical therapy |
|
broad role for PCBP1 and PCBP2 in delivering iron to cytosolic nonheme iron enzymes |
|
a feedback inhibitor of mitochondrial antiviral signaling that facilitates its degradation after viral infection |
|
PCBP1 and PCBP2 may serve as iron chaperones to multiple classes of cytosolic nonheme iron enzymes and may have a particular role in restoring metal cofactors that are spontaneously lost in iron deficient cells |