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FLASH GENE
Symbol PPP1R3D contributors: - updated : 24-05-2005
HGNC name protein phosphatase 1, regulatory subunit 3D
HGNC id 9294
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   highly
Nervousbrain    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscularstriatumcardiac  
Nervousperipherous   
cells
SystemCellPubmedSpeciesStageRna symbol
Nervousneuron
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a single consensus sequence in PSD95/DLG/ZO-1 and properties expected of a scaffolding protein localized to the cell membrane
  • HOMOLOGY
    interspecies homolog to murine Ptg
    Homologene
    FAMILY
    CATEGORY chaperone/stress , enzyme , regulatory
    SUBCELLULAR LOCALIZATION     plasma membrane
    text dendritic spines
    basic FUNCTION
  • serine/threonine protein phosphatase, modulator of PP1 enzymatic activity
  • glycogen targeting subunit 6 of protein phosphatase 1
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • PP1
  • interacting with ADRA2B (contributing to cell surface stabilization of the receptor)
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS