protein
| SEC13/31 complex |
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SAR1 |
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during COPII assembly, SAR1A deforms the membrane and recruits the SEC23A-SEC24A complex (SEC23/24), which is the primary cargo-binding adaptor for the system |
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CFDP1, Sec23 homolog A (SEC23A), and nuclear receptor binding SET domain protein 1 (NSD1), contain consensus GTF2I binding sites in their proximal promoters |
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CREB3L2-mediated SEC23A pathway is involved in regulation of intracellular procollagen trafficking |
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target of CREB3L2 is SEC23A, one of the coat protein complex II components |
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endoplasmic reticulum stress reduces COPII vesicle formation and modifies SEC23A cycling at ER Exit Sites |
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activated CREB3L2 accelerates cartilage matrix protein secretion through the up-regulation of SEC23A, which is responsible for protein transport from the ER to the Golgi apparatus and is a target of CREB3L2 |
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novel regulatory mechanisms of SOX9 for controlling the secretion of cartilage matrix proteins through the activation of CREB3L2-SEC23A signaling during chondrogenesis |
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