SUBCELLULAR LOCALIZATION
| intracellular
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| intracellular,cytoplasm,organelle,mitochondria,outer
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| intracellular,cytoplasm,organelle,membrane
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| intracellular,cytoplasm,organelle,endoplasmic reticulum
|
| intracellular,nucleus,nucleolus
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basic FUNCTION
| converting free long-chain fatty acids into fatty acyl CoA esters |
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functioning in mediating fatty acids-induced glioma cell growth |
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utilizing a wide range of saturated fatty acids with a preference for C16-C18 unsaturated fatty acids |
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epidermal ACSL5 expression might be involved in differentiation and the stress response of keratinocytes |
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critical to the expression of tumor-related factors including midkine (MDK), a heparin-binding growth factor frequently overexpressed in cancer |
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is an important branch point in hepatic fatty acids (FAs) metabolism |
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may play a role in the apoptosis that takes place in systemic lupus erythematosus |
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catalyzes the synthesis of long-chain fatty acid thioesters and is physiologically involved in pro-apoptotic sensing of enterocytes |
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mediates antiproliferative activities via WNT2B palmitoylation with diminished Wnt activity |
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is involved in enterocytic differentiation and maturation by regulating both pro-apoptotic and anti-proliferative effects |