Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol CDC42EP3 contributors: npt/mct - updated : 24/10/2008
HGNC name CDC42 effector protein (Rho GTPase binding) 3
HGNC id 16943
EXPRESSION
Type ubiquitous
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   highly
Digestiveliver   lowly
Endocrinepancreas    
Lymphoid/Immunelymph node   highly
Nervousbrain   lowly
Reproductivemale systemprostate  highly
Urinarykidney    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialsecretoryglandularendocrine 
Epithelialsecretoryglandularexocrine 
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a CRIB (Cdc42/Rac interactive-binding) domain
  • a conserved 12-residue BORG homology-1 (BH1) domain in its N terminus
  • an 11-amino acid BH2 domain in its central region
  • a 22-residue BH3 domain in its C terminus
  • HOMOLOGY
    interspecies homolog to Drosophila CG7526
    homolog to C.elegans Y64G10A7
    Homologene
    FAMILY
  • CDC42 binding protein family
  • BORG/CEP family
  • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,cytoplasm,cytoskeleton
    basic FUNCTION regulator of mammalian septin organization
    CELLULAR PROCESS cell organization/biogenesis
    PHYSIOLOGICAL PROCESS
    text cell shape and cell size control
    PATHWAY
    metabolism
    signaling signal transduction
    a component
    INTERACTION
    DNA
    RNA
    small molecule nucleotide,
  • GTP
  • protein
  • binding to TC10 and CDC42 and cytoskeletal regulatory protein
  • bind to septin GTPases
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS