basic FUNCTION
| regulating the tight junction assembly in epithelia |
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counter-receptor for LFA1 controling transmigration during leukocyte recruitment |
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cell adhesion molecule of the immunoglobulin superfamily involved in platelet adhesion, secretion |
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plays a critical role in the function of endothelial cells and in platelet adhesion to inflamed endothelium |
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having with NKkappa B a function in the initiation of inflammatory thrombosis |
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JAM1, JAM2, JAM3 expressions on the lymphatic endothelium may contribute to both seal the cell-cell contact at interendothelial junctions |
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play an important role in the assembly and maintenance of tight junctions and in the establishment of epithelial cell polarity |
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in addition to the previously reported role of F11R in the initiation of plaque formation, F11R plays also an important role in the subsequent growth of atherosclerotic plaques |
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restricts intestinal epithelial cell (IEC) proliferation in a dimerization-dependent manner, by inhibiting AKT1-dependent CTNNB1 activation |
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unique tight junction (TJ) transmembrane protein that under basal conditions maintains endothelial cell-cell interactions but under inflammatory conditions acts as a leukocyte adhesion molecule |
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potential role in controlling perijunctional actin cytoskeleton in addition to its previously reported role in regulating claudin proteins and small-molecule permeability |
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cell adhesion molecule found on the surface of human platelets |
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key regulator of mesoangioblasts (MABs) extravasation |
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serve a crucial role in the proliferation, differentiation, and tube-like formation of epithelial cells during angiogenesis |