protein
| association with six other proteins, metaxins 1, and 2, CHCHD3, CHCHD6 and DNAJC11 SAMM50 (putative role in protein import related to maintenance of mitochondrial structure) |
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PARP1 interactor (promotes and is required for PARP1 mitochondrial localization) |
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interaction between PINK1 and Mitofilin |
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functional link between DISC1 and Mitofilin for the normal mitochondrial function |
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MINOS1 interacts with TOMM40 and SAMM50 independently and the core subunit IMMT is involved in biogenesis of outer membrane beta-barrel proteins |
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APOOL physically interacts with several subunits of the MINOS complex, namely IMMT, MINOS1, and SAMM50 |
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interacts with mitochondrial transcription factors TFAM and TFB2M |
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SLC25A46 interacts with the inner membrane remodeling protein mitofilin (IMMT) |
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direct interaction between IMMT and CHCHD3, which is crucial for their stabilization in mammals |
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IMMT homeostasis regulated by YME1L1 is central to the MICOS assembly, which is required for maintenance of mitochondrial morphology and organization of mtDNA nucleoids |
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IMMT and CHCHD6 directly interacted with SAMM50 |
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IMMT is a PRKACA substrate |
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transiently interacts with PINK1, and IMMT downregulation leads to a reduction in PINK1 and mislocalization of PRKN |