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FLASH GENE
Symbol APOL3 contributors: mct - updated : 08-04-2011
HGNC name apolipoprotein L, 3
HGNC id 14868
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart    
Nervousbrain    
Reproductivemale systemprostate  highly
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period fetal, pregnancy
Text placenta,liver
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
conserved amphipathic alpha helices
HOMOLOGY
Homologene
FAMILY APOL family
CATEGORY transport carrier
SUBCELLULAR LOCALIZATION extracellular
    intracellular
intracellular,cytoplasm,organelle,membrane
basic FUNCTION
  • may be affecting the movement of lipids in the cytoplasm or allow the binding of lipids to
  • organelles.
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility to prostate cancer (HPC)
    Variant & Polymorphism SNP rs2097365, rs2017329, rs2097465, having the strongest association with HPC risk
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS