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FLASH GENE
Symbol IGSF5 contributors: mct/npt - updated : 03-07-2008
HGNC name immunoglobulin superfamily, member 5
HGNC id 5952
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivefemale systemplacenta   
Urinarykidney    
cells
SystemCellPubmedSpeciesStageRna symbol
Blood/Hematopoieticprogenitor cell
Reproductivegerm cell
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • an intracellular Ig-like domain with potential N glycosylation site
  • a transmembrane segment
  • a cytoplasmic tail
  • two PDZ domains
  • conjugated GlycoP
    HOMOLOGY
    Homologene
    FAMILY
  • immunoglobulin superfamily
  • CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION     plasma membrane,junction,tight
    basic FUNCTION
  • implicated in the regulation of paracellular permeability and the signalings of hepatocyte growth factor
  • implicated in the reorganization of cell junctions
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interacting with MAGI1
  • interacting with LNX1(directly binds the second PDZ domain of LNX1 through its carboxyl terminus)
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS