basic FUNCTION
| may be important for both mitogen-stimulated fibroblast proliferation and skeletal muscle cell differentiation |
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acting as a transcriptional stimulator of VEGF by regulating VEGF promoter activity through binding to Sp1 site and may play an important role in the regulation of VEGF under hypoxia |
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playing a role in the control of the transcription of the VEGF gene, in ocular vascular endothelial cells |
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playing essential roles in mediating biological functions of YAP1 |
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required for RCAN-1L expression through binding to the M-CAT site in its promoter |
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required for trophectoderm development |
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early transcription factor required for specification and development of the trophectoderm lineage, which includes expression of CDX2 |
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may also function to promote angiogenic response |
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plays an important role in transcriptional regulation of angiogenic genes in hypoxic endothelial cells, and key regulator of angiogenesis in response to hypoxia |
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mammalian Tead proteins regulate cell proliferation and contact inhibition as a transcriptional mediator of Hippo signaling |
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play an important role in both endothelial cells and cardiomyocytes |
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TEAD4-driven increase of VEGFB plays an important role in communication between the endothelium and myocardium |
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plays an important role in endothelial cell function by regulating angiogenesis |
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stimulates promoter activity through an insulin response element and also mediates the effects of insulin on gene expression |
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is not required for specification of the trophectoderm lineage |
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plays a crucial role in maintaining energy homeostasis during preimplantation development |