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FLASH GENE
Symbol PIGB contributors: mct - updated : 10-09-2019
HGNC name phosphatidylinositol glycan anchor biosynthesis, class B
HGNC id 8959
EXPRESSION
Type widely
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveesophagus   highly
Lymphoid/Immunelymph node   highly
Urinarybladder   highly
cells
SystemCellPubmedSpeciesStageRna symbol
Blood/Hematopoieticgranulocyte
cell lineage stem cell hematopoietic
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
a glycosyltransferase motif
HOMOLOGY
Homologene
FAMILY dolichol-phosphate-mannose (Dol-P-Man) dependent mannosyltransferases family
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,membrane
intracellular,cytoplasm,organelle,endoplasmic reticulum
basic FUNCTION
  • glycosyl-phosphatidylinositol (GPI) anchor synthesis,class B, involved in transferring the third mannose of the GPI anchor for cell surface proteins
  • transfers the third mannose to the GPI precursor
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) PIGBD
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS