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FLASH GENE
Symbol RABGGTB contributors: mct/npt - updated : 31-03-2009
HGNC name Rab geranylgeranyltransferase, beta subunit
HGNC id 9796
EXPRESSION
Type ubiquitous
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivesalivary gland   highly
Hearing/Equilibriumear   highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Connectivebone  highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
mono polymer dimer
HOMOLOGY
interspecies ortholog to rattus Rabggtb
ortholog to murine Mbeta,Rabggtb
ortholog to yeast S.pombe spbeta
ortholog to C.elegans
Homologene
FAMILY
  • protein prenyltransferase subunit beta family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • regulator of vesicular transport steps in endocytic and secretory pathways
  • having a post-transcriptional regulation of its gene expression (Chinpaisal 1997)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • beta subunit forming a dimer with alpha subunit
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interaction with CHODL (Claessens 2008)
  • cell & other
    REGULATION
    activated by Rab escort proteins (REP1,CHML)
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS