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FLASH GENE
Symbol SLC25A16 contributors: - updated : 18-03-2006
HGNC name solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16
HGNC id 10986
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Endocrineadrenal gland   highly
 pancreas    
Nervousbrain    
Reproductivemale systemprostate   
Respiratoryrespiratory tractlarynx  highly
Urinarykidney    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialsecretoryglandularendocrine 
Epithelialsecretoryglandularexocrine 
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
three tandemly repeated mitochondrial carrier protein domains
HOMOLOGY
interspecies homolog to Drosophila CG1628
homolog to C.elegans T10F2.2
intraspecies homolog to adenine nucleotide translocator
Homologene
FAMILY solute carrier family 25,mitochondrial
CATEGORY antigen , transport carrier
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,mitochondria,inner
basic FUNCTION
  • facilitating the rapid transport and exchange of molecules betwenn the cytosol and the mitochondrial matrix space
  • required for the accumulation of coenzyme A in the mitochondrial matrix
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS active transport , mitochondrial transport
    text energy transfer
    PATHWAY
    metabolism energetic
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility Graves disease (possible role)
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS