basic FUNCTION
| involved in the suppression of transcription |
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indispensable for early embryonic development and cell proliferation (Li 2006) |
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involved in negative regulation of VEGF and may represent a novel repressor of VEGF transcription (Harper 2007) |
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displays a suppressive effect on the transcription (Li 2009) |
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a pleiotropic factor that has a role in hematopoiesis, brain development and cancers (Li 2009) |
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essential factor acting for the promotion of the cell cycle and thus maintenance in the progenitor stage (Khalfallah 2009) |
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required for the myelinating function of differentiated oligodendrocytes (Howng 2010) |
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required for the conversion of oligodendrocytes from the premyelinating to the myelinating state (Howng 2010) |
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involved in negative regulation of PDGFRB via its interaction with MYC and may represent a novel repressor of PDGFRB transcription |
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involved in negative regulation of vascular endothelial growth factor (VEGF) and may represent a novel repressor of VEGF transcription |