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FLASH GENE
Symbol SNRPA contributors: - updated : 18-02-2006
HGNC name small nuclear ribonucleoprotein polypeptide A
HGNC id 11151
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver   highly
Endocrinepancreas   highly
Lymphoid/Immunespleen   highly
 thymus   highly
Reproductivemale systemprostate  moderately
Respiratorylung   moderately
Urinarykidney   moderately
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES Hydrophilic
STRUCTURE
motifs/domains
  • two RNA recognition motif (RRM) domains
  • a hydrophilic region
  • an internal sequence duplication
  • a RNP consensus domain common to RNA-binding proteins
  • conjugated RiboP
    HOMOLOGY
    interspecies ortholog to murine Snrpa
    homolog to rattus Rn.9347
    homolog to Xenopus Xl.5225
    homolog to zebrafish Dr.1930
    homolog to C.elegans K08D10.3
    Homologene
    FAMILY U1 A/B" family
    CATEGORY RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION may be involved in coupled pre-mRNA splicing and
    polyadenylation process
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component involved in spliceosome complex
    INTERACTION
    DNA
    RNA binding to stem loop II of U1 snRNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS