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FLASH GENE
Symbol GNG5 contributors: - updated : 13-02-2006
HGNC name guanine nucleotide binding protein (G protein), gamma 5
HGNC id 4408
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver   highly
Lymphoid/Immunespleen   highly
Nervousbrain   moderately
Reproductivemale systemprostate  moderately
Respiratorylung   moderately
Urinarykidney   moderately
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
conjugated LipoP
mono polymer heteromer , trimer
HOMOLOGY
interspecies ortholog to murine Gng5
homolog to Xenopus Xl.7680
homolog to zebrafish Dr.9659
homolog to C.elegans K02A4.2
Homologene
FAMILY G protein gamma family
CATEGORY receptor membrane G
SUBCELLULAR LOCALIZATION     plasma membrane
basic FUNCTION
  • modulating or transducing various transmembrane signaling systems
  • required for the GTPase activity and for the replacement of GDP by GTP
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling signal transduction
    a component heterotrimeric G-protein GTPase, gamma-subunit
    INTERACTION
    DNA
    RNA
    small molecule nucleotide,
    GDP, GTP
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS