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FLASH GENE
Symbol SSR2 contributors: - updated : 18-01-2006
HGNC name signal sequence receptor, beta (translocon-associated protein beta)
HGNC id 11324
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Lymphoid/Immunethymus   highly
Reproductivefemale systemovary  highly
 male systemprostate  highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / hematopoieticbone marrow   
Connectivebone   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
glycosylated
mono polymer heteromer , tetramer
HOMOLOGY
Homologene
FAMILY TRAP-beta family
CATEGORY receptor
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,mitochondria,matrix
intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
basic FUNCTION
  • signal sequence receptor, beta, involved in protein translocation process
  • part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • glycosylated membrane protein constituent of endoplasmic reticulum
  • heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS