Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
tumoral
|  
|  
| --other
|  
|
disturbance of circadian expression in advanced gastric carcinoma, may be relevant for chronomodulated 5-fluoro-uracil-chemo therapy | constitutional
|  
| deletion
|  
|  
|
hemizygous deletions in autism spectrum disorder with severe speech delay | constitutional
|  
|  
|  
| loss of function
|
in DPYD deficient patients, and fluoropyrimidines combined with other therapies such as radiotherapy might be particularly toxic for such patients | constitutional
|  
|  
|  
| gain of function
|
in liver may be involved in acquired resistance to 5-FU | |