basic FUNCTION
| may be involved in growth regulation of B-cells |
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assembling with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation |
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essential role for CD19, independent of the costimulatory molecule CD21, in amplifying early B cell activation events in response to membrane-bound ligand stimulation |
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PIK3AP1 and CD19 have complementary roles in BCR-mediated PI3K activation, thereby, at least in part, contributing to B-cell development |
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response regulator of B lymphocytes, regulates wound healing through hyaluronan-induced TLR4 signaling |
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role for complement receptors in B-cell memory independent of CD19 |
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B-cell transmembrane molecule that is critical for B-cell activation |
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functions in a complex with CD21, CD81, and CD225 to signal with the B cell receptor upon antigen recognition |
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is critically involved in establishing intrinsic B cell signaling thresholds through modulating both B cell receptor-dependent and independent signaling |
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CD19 positively regulates B cell activation, augmenting signals delivered through the BCR complex |
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CD19 is present throughout the cell life cycle and is uniformly expressed in leukemias |