basic FUNCTION
| playing a central role in regulating the level of blood glucose by controlling the rate of hepatic glucose production and insulin secretion |
|
playing a role in the generation of precursor metabolites and energy |
|
invovled in the regulation of blood pressure |
|
is required for control of lipid metabolism during the adaptive metabolic response to fasting |
|
activation of GCGR induced CTNNB1 stabilization and activated CTNNB1-mediated transcription |
|
GCGR is expressed in the human colon and, once activated by exogenous GCG, mediates an inhibitory effect on large intestine motility through NO neural release |
|
GLP1R, GIPR, and GCGR internalize with differential properties |