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FLASH GENE
Symbol UBA52 contributors: - updated : 27-12-2005
HGNC name ubiquitin A-52 residue ribosomal protein fusion product 1
HGNC id 12458
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • encoding a fusion protein consisting of ubiquitin at the N terminus and ribosomal protein L40 at the C terminus
  • zinc finger like domain
    • HOMOLOGY
    interspecies ortholog to murine Uba52
    homolog to Drosophila Ubi-p63E
    homolog to C.elegans ubq-2
    homolog to yeast S.cerevisiae Ubi1/Ubi2
    Homologene
    FAMILY L40E family of ribosomal proteins
    CATEGORY RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    intracellular,nucleus
    basic FUNCTION
  • involved in the ATP-dependent selective degradation of cellular proteins, the maintenance of chromatin structure, the regulation of gene expression, the stress response, and ribosome biogenesis
    • CELLULAR PROCESS nucleotide, chromatin organization, remodeling
    protein, translation/synthesis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component ribosomal subunit
    INTERACTION
    DNA
    RNA binding
    small molecule metal binding,
    zinc Zn2+
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS