basic FUNCTION
| DNA synthesis |
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cytokine-mediated signal transduction (potential cytokine receptor signaling) |
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associates with hepatocyte growth factor-regulated substrate and plays a key role in the endosomal sorting machinery |
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involved in growth factor and cytokine signaling as well as receptor degradation, and they form complexes with a number of endocytic proteins, including HARS and EPS15 |
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function prominently in ER-to-Golgi trafficking, most likely through direct interactions with the COPII complex |
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endosomal protein involved in sorting activated RTKs for lysosomal degradation |
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involved in growth factor and cytokine signaling as well as receptor degradation, and they form complexes with a number of endocytic proteins, including HGS and EPS15 |
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in addition to their roles in signaling and endocytosis, function prominently in ER-to-Golgi trafficking, most likely through direct interactions with the COPII complex |