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FLASH GENE
Symbol PECR contributors: npt - updated : 23-09-2006
HGNC name peroxisomal trans-2-enoyl-CoA reductase
HGNC id 18281
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   lowly
Digestiveliver   highly
Nervousbrain    
Respiratorylung    
Urinarykidney   highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / Hematopoieticbone marrow   
Connectivebone   
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • peroxisomal targeting signal (AKL)
  • C terminus short chain dehydrogenase/reductase
  • HOMOLOGY
    interspecies ortholog to murine Pecr
    homolog to Drosophila CG1696
    homolog to C.elegans F45E12.1
    Homologene
    FAMILY
  • 3 beta hydroxysteroid dehydrogenase/isomerase family
  • short-chain deshydrogenase/reductases (SDR) family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,peroxisome
    basic FUNCTION
  • fatty acids chain elongation pathway
  • reducing trans-2-enoylCoAs of from 6:1 to 16:1
  • CELLULAR PROCESS cell life, cell death/apoptosis
    PHYSIOLOGICAL PROCESS
    text apoptosis regulator
    PATHWAY
    metabolism lipid/lipoprotein
    signaling
    enterobactin biosynthesis
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS